Organic Chemistry

Organic Chemistry

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By (author) Jonathan Clayden, By (author) Nick Greeves, By (author) Stuart Warren

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  • Publisher: Oxford University Press
  • Format: Paperback | 1264 pages
  • Dimensions: 198mm x 276mm x 50mm | 2,400g
  • Publication date: 4 May 2012
  • Publication City/Country: Oxford
  • ISBN 10: 0199270295
  • ISBN 13: 9780199270293
  • Edition: 2, Revised
  • Edition statement: 2nd Revised edition
  • Illustrations note: 3600 colour line drawings
  • Sales rank: 31,457

Product description

Inspiring and motivating students from the moment it published, Organic Chemistry has established itself in just one edition as the students' choice of organic chemistry text. This second edition takes all that has made Organic Chemistry the book of choice, and has refined and refocused it to produce a text that is even more student-friendly, more coherent and more logical in its presentation than before. At heart, the second edition remains true to the first, being built on three principles: An explanatory approach, through which the reader is motivated to understand the subject and not just learn the facts; A mechanistic approach, giving the reader the power to understand compounds and reactions never previously encountered; An evidence-based approach, setting out clearly how and why reactions happen as they do, giving extra depth to the reader's understanding. The authors write clearly and directly, sharing with the reader their own fascination with the subject, and leading them carefully from topic to topic. Their honest and open narrative flags pitfalls and misconceptions, guiding the reader towards a complete picture of organic chemistry and its universal themes and principles. Enriched with an extensive bank of online resources to help the reader visualise the structure of organic compounds and their reaction mechanisms, this second edition reaffirms the position of Organic Chemistry as the essential course companion for all organic chemistry students. Online Resource Centre For students: A range of problems to accompany each chapter For registered adopters of the text: Figures from the book in electronic format

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Author information

Stuart Warren is a former lecturer in the Department of Chemistry at the University of Cambridge and Fellow of Churchill College, Cambridge. A graduate of Trinity College, Cambridge, Stuart completed his PhD at Cambridge with Malcolm Clark before carrying out post-doctoral research at Harvard University. He became a teaching fellow at Churchill College in 1971, and remained a lecturer and researcher at Cambridge until his retirement in 2006.

Review quote

It is a credit to the authors that a textbook that I have adored for so many years has undergone such a substantial overhaul and yet still retains the features that made it quite so attractive to students in the first place. This is a book that will continue to inspire students of organic chemistry for many years to come. Even if you already have the first edition, I am happy to recommend that you invest in this new version you will not be disappointed. John Hayward, in Chemistry World, December 2012 Review from previous edition This is a book we have all been waiting for! It is based on sound mechanistic reasoning and contains thousands of useful examples for teaching. Its style is approachable and covers both fundamental and more advanced material. Adam Nelson, Lecturer, University of Leeds Review from previous edition Represents a milestone in the field of organic chemistry textbooks... This is the first organic textbook that could be used in some shape or form on almost every organic chemistry course in any UK undergraduate programme... I soon expect to be hearing "You can look it up in Clayden" ringing from lectures and tutorials, and for many years to come. Andrew Boa in The Times Higher Education, 2001

Table of contents

1. What is organic chemistry? ; 2. Organic structures ; 3. Determining organic structures ; 4. Structure of molecules ; 5. Organic reactions ; 6. Nucleophilic addition to the carbonyl group ; 7. Delocalization and conjugation ; 8. Acidity, basicity, and pKa ; 9. Using organometallic reagents to make C-C bonds ; 10. Nucleophilic substitution at the carbonyl group ; 11. Nucleophilic substitution at C=O with loss of carbonyl oxygen ; 12. Equilibria, rates and mechanisms ; 13. 1H NMR: Proton nuclear magnetic resonance ; 14. Stereochemistry ; 15. Nucleophilic substitution at saturated carbon ; 16. Conformational analysis ; 17. Elimination reactions ; 18. Review of spectroscopic methods ; 19. Electrophilic addition to alkenes ; 20. Formation and reactions of enols and enolates ; 21. Electrophilic aromatic substitution ; 22. Conjugate addition and nucleophilic aromatic substitution ; 23. Chemoselectivity and protecting groups ; 24. Regioselectivity ; 25. Alkylation of enolates ; 26. Reactions of enolates with carbonyl compounds: the aldol and Claisen reactions ; 27. Sulfur, silicon and phosphorus in organic chemistry ; 28. Retrosynthetic analysis ; 29. Aromatic heterocycles 1: structures and reactions ; 30. Aromatic heterocycles 2: synthesis ; 31. Saturated heterocycles and stereoelectronics ; 32. Stereoselectivity in cyclic molecules ; 33. Diastereoselectivity ; 34. Pericyclic reactions 1: cycloadditions ; 35. Pericyclic reactions 2: sigmatropic and electrocyclic reactions ; 36. Participation, rearrangement and fragmentation ; 37. Radical reactions ; 38. Synthesis and reactions of carbenes ; 39. Determining reaction mechanisms ; 40. Organometallic chemistry ; 41. Asymmetric synthesis ; 42. Organic chemistry of life ; 43. Organic chemistry today