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    Metal-on-Metal Bearings: A Clinical Practicum (Hardback) Edited by Lynne C. Jones, Edited by Warren O. Haggard, Edited by A. Seth Greenwald

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    DescriptionThis book addresses the background and significance of the factors potentially influencing the clinical and biological outcomes of metal-on-metal hip implants. Metal-on-metal bearings were introduced and evaluated as an alternative to other bearing couples, particularly metal-on-polyethylene, due to their enhanced wear resistance as determined in laboratory testing. Initially, reports of short-term clinical outcomes were favorable and an increasing number of metal-on-metal prostheses were implanted. Subsequently, isolated case findings describing adverse tissue responses around the articulation became the harbinger of an increasing number of reports describing pseudotumors and other significant lymphocytic-based responses associated with metal-on-metal prostheses. Questions have been raised as to whether this is an implant, design, or patient-specific response. The reasons why some patients have a negative biological response and pathology while others do not remain to be determined, but tens of thousands of patients in the US, the UK, and around the world are considered to be at risk. Leading researchers and clinicians describe the issues related to the nature of the biological and pathological responses and the protocols that should be followed to determine if an adverse response is occurring. This book is essential reading for researchers, engineers, and orthopaedic surgeons who are involved in the design, evaluation, and implantation of metal-on-metal prostheses.


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    Title
    Metal-on-Metal Bearings
    Subtitle
    A Clinical Practicum
    Authors and contributors
    Edited by Lynne C. Jones, Edited by Warren O. Haggard, Edited by A. Seth Greenwald
    Physical properties
    Format: Hardback
    Number of pages: 220
    Width: 155 mm
    Height: 235 mm
    Thickness: 18 mm
    Weight: 489 g
    Language
    English
    ISBN
    ISBN 13: 9781461489986
    ISBN 10: 1461489989
    Classifications

    Warengruppen-Systematik des deutschen Buchhandels: 16960
    BIC E4L: HEA
    B&T Book Type: NF
    BIC subject category V2: MBGR
    Nielsen BookScan Product Class 3: S6.3
    B&T Modifier: Region of Publication: 01
    LC subject heading: ,
    BIC subject category V2: MNS
    LC classification: QH506
    B&T Merchandise Category: SCI
    B&T General Subject: 710
    B&T Modifier: Academic Level: 02
    Ingram Subject Code: TE
    B&T Modifier: Text Format: 06
    BISAC V2.8: SCI049000, TEC021000
    BIC subject category V2: TGM
    BISAC V2.8: TEC009000
    LC classification: R857.M3
    LC subject heading:
    DC22: 610.28
    BISAC V2.8: MED029000
    BIC subject category V2: TDM
    LC subject heading:
    BIC subject category V2: MQW
    BISAC V2.8: MED065000
    LC subject heading:
    BIC subject category V2: TGBF
    Libri: BIOM4500, MEDI6412, OPER2068, TRAO3000
    DC22: 617.5/810592
    Libri: GELE5042, HUEF5000, P0039827
    LC subject heading: ,
    DC23: 617.5810592
    LC subject heading:
    LC classification: R856-857, TA401-492, RD701-811, TA459-492, TA467, TJ1075-1081, RD549 .M48 2014
    LC subject heading:
    Thema V1.0: TGM, MBGR, TDPM, MQW, MNS, TGBF
    Edition
    1
    Edition statement
    2014 ed.
    Illustrations note
    20 black & white illustrations, 26 colour illustrations, 11 black & white tables, biography
    Publisher
    Springer-Verlag New York Inc.
    Imprint name
    Springer-Verlag New York Inc.
    Publication date
    13 November 2013
    Publication City/Country
    New York, NY
    Back cover copy
    This book addresses the background and significance of the factors potentially influencing the clinical and biological outcomes of metal-on-metal hip implants.Metal-on-metal bearings were introduced and evaluated as an alternative to other bearing couples, particularly metal-on-polyethylene, due to their enhanced wear resistance as determined in laboratory testing.Initially, reports of short-term clinical outcomes were favorable and an increasing number of metal-on-metal prostheses were implanted. Subsequently, isolated case findings describing adverse tissue responses around the articulation became the harbinger of an increasing number of reports describing pseudotumors and other significant lymphocytic-based responses associated with metal-on-metal prostheses. Questions have been raised as to whether this is an implant, design, or patient-specific response. The reasons why some patients have a negative biological response and pathology while others do not remain to be determined, but tens of thousands of patients in the US, the UK, and around the world are considered to be at risk. Leading researchers and clinicians describe the issues related to the nature of the biological and pathological responses and the protocols that should be followed to determine if an adverse response is occurring. This book is essential reading for researchers, engineers, and orthopaedic surgeons who are involved in the design, evaluation, and implantation of metal-on-metal prostheses.Presents an historical overview of the use of metal-on-metal articulationsCollects for the first time the information necessary to assess clinically and biologically relevant patient outcomes Addresses the practical questions that are being raised by surgeons, researchers, and engineers Features contributions by acknowledged leaders in their fieldsDescribes what the clinician needs to know in order to practice evidence-based medicineProjects directions for clinical, biological, and biomechanical research efforts"
    Table of contents
    Preface Part I: Introduction Chapter 1: Introduction Chapter 2: Bearing Surfaces for Joint Replacement: New Materials or New Problems? Part II: Clinical Chapter 3: Outcome Studies for Metal-on-Metal Bearings: What Evidence-Based Medicine Tells Us Chapter 4: Metal Reactivity: Its Influence on Primary and Revision Outcomes Chapter 5: Are metal ion levels a trigger for surgical intervention? Chapter 6: Metal Sensitivity: Is it possible to Determine Clinically? Part III: Biology Chapter 7: Wound healing, chronic inflammation, and immune responses Chapter 8: Benign Responses to Orthopaedic Implants: Really? Chapter 9: What does the Histology Tell Us? Part IV: Biomechanics Chapter 10: Why metal-on-metal -what laboratory tests have shown us Chapter 11: What do the Retrievals really tell us? Future Directions Index