The Laboratory Swine

The Laboratory Swine

Paperback Laboratory Animal Pocket Reference

By (author) Aage Kristian Olsen Alstrup, By (author) Peter J.A. Bollen, By (author) Axel Kornerup Hansen, Series edited by Mark A. Suckow

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  • Publisher: CRC Press Inc
  • Format: Paperback | 138 pages
  • Dimensions: 157mm x 231mm x 8mm | 227g
  • Publication date: 22 February 2010
  • Publication City/Country: Bosa Roca
  • ISBN 10: 1439815283
  • ISBN 13: 9781439815281
  • Edition: 2, Revised
  • Edition statement: 2nd Revised edition
  • Illustrations note: 31 colour illustrations, 33 black & white tables
  • Sales rank: 1,055,381

Product description

Since the popular first edition was published more than a decade ago, the number of swine used in toxicity studies has increased as an alternative to commonly used non-rodent species, such as dogs and primates. A volume in the Laboratory Animal Pocket Reference Series, The Laboratory Swine, Second Edition maintains the high standard set by the previous edition and is poised to continue its legacy as the premier laboratory reference on the care and use of swine in the laboratory. Emphasizes Humane Care and Use of Laboratory Swine Addressing the biology, husbandry, management, veterinary care and research applications of both large and miniature swine, this color reference is a complete source of information on the species. It is thoroughly updated and includes a major revision to the anesthetics section. It also places a heightened focus on animal welfare and addresses important considerations related to genetically modified swine. The book is divided into six parts: Important Biological Features examines everything from different breeds and behavior, to anatomical and physiological features, as well as digestive, cardiovascular, and pulmonary systems Husbandry addresses housing, nutrition, sanitation, transportation, and more Management and Quality Assurance looks at the impact of infections on animal research using swine, zoonotic diseases, legal regulations, genetic monitoring, and more Veterinary Care covers a variety of topics, such as clinical examination, diseases, pain recognition, and post-operative management Experimental Techniques addresses restraint, sampling techniques, basic surgical procedures, and other issues Resources provides extensive references for further study, including handbooks, journals, and websites The Laboratory Swine, Second Edition is ideal for animal caretakers, technicians, investigators, and laboratory animal veterinarians as a single-source reference that contributes to the humane care and use of swine in research.

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Author information

Peter J.A. Bollen, Ph.D., is the head of Biomedical Laboratory, the central animal facility of the University of Southern Denmark, Odense, where he also received his Ph.D. degree. He studied experimental zoology and laboratory animal science in Utrecht, the Netherlands, and laboratory animal science in London. Axel Kornerup Hansen, Dr. Vet. Sci. DVM, is a professor of Laboratory Animal Science and Welfare at the Royal Veterinary and Agricultural University in Copenhagen, Denmark, from which he also graduated. He is the head of the Department of Veterinary Disease Biology, one of the four veterinary departments at the Faculty of Life Sciences of the University of Copenhagen, Denmark. Aage Kristian Olsen Alstrup, Ph.D. DVM, is a graduate of the Royal Veterinary and Agricultural University in Copenhagen, Denmark, from which he also received his Ph.D. degree. He is responsible for animal models at the PET Center of Aarhus University Hospital, Denmark.

Review quote

The second editions of The Laboratory Swine and The Laboratory Rabbit are enhanced with full color illustrations. Both books have an extensively updated section on anesthesia, analgesia and use of humane techniques in animal research. The Laboratory Swine also provides new information on the use of genetically modified swine. Both new additions are valuable additions to the laboratory animal library collection. -Nanette Kleinman, in ACLAM Newsletter, September 2010 This second edition provides a multitude of information that is greatly aided by the use of many color photographs. It would be a valuable addition to facility libraries that are readily available to animal technicians and caretakers. -Journal of the American Association of Laboratory Animal Science, 2010

Table of contents

Important biological features Breeds The Landrace The Yorkshire, or Large White The Duroc The Hampshire The Pietrain Other Breeds Hybrid Breeds Miniature Breeds The Vietnamese Potbelly Pig The Ossabaw Island Hog Nomenclature Behavior Anatomical and physiological features Integument and Skeleton Digestive System Abdominal Organs Cardiovascular System Pulmonary System Lymphatic and Endocrine System Normative values Husbandry Housing Environmental conditions Temperature and Humidity Ventilation Illumination Noise Environmental enrichment Group Housing Individual Housing Nutrition Nutrient Requirements Feeding Levels Sanitation Frequency Methods Transportation Record keeping Securing welfare Management and quality assurance Microbiological monitoring Infections in Swine and Their Impact on Experiments Pathological Changes, Clinical Disease, and Mortality Immunomodulation Physiological Modulation Competition between Microorganisms within the Animal Interference with Reproduction Interference with Oncogenesis Contamination of Biological Products Impact of the Normal Flora Zoonotic Diseases Legal Regulations Precautions to Prevent Infections Rederivation Barrier Protection Health Monitoring Common Findings in Health Monitoring Genetic monitoring Accreditation AAALAC International ISO 9000 Veterinary care Clinical examination of swine Microbiological sampling Diseases of swine Therapeutic treatment Pathological examination Anesthesia and analgesia Acclimatization Clinical Examination Prior to Anesthesia Preoperative Fasting Premedication Ear Vein Catheter Induction of Anesthesia Endotracheal Intubation Cricothyrotomy Artificial Ventilation Thermal Support Maintenance of Anesthesia Inhalation Anesthesia Halothane Isoflurane Desflurane Sevoflurane Enflurane Nitrous Oxide Injectable Anesthesia Propofol Ketamine and Other Dissociatives Barbiturates Adrenoreceptor (alpha2) Agonists Benzodiazepines Alpha-Chloralose Medetomidine-Butorphanol-Ketamine (MBK) Supplementary Analgesia Fluid Infusion Depth of Anesthesia Monitoring during Anesthesia Neuromuscular Blocking Agents Postoperative Management Clinical Signs of Postoperative Pain Postoperative Analgesics Anesthetic Emergencies Laryngospasm and Edema Euthanasia Experimental techniques Restraint Sampling techniques Blood Sampling Urine and Feces Cerebrospinal Fluid Bile and Pancreatic Excretions Administration of compounds Basic surgical procedures Catheterization The Carotid Artery and the Internal Jugular Vein The Carotid Artery The Internal Jugular Vein The External Jugular Vein The Cephalic Vein The Femoral Artery and Vein Laparotomy Portal Vein Cannulation The Hepatic Vein The Pancreatic Duct Exteriorization of Catheters Catheter Sizes and Material Catheter Maintenance Safety testing of chemicals and drugs Dermal Toxicology Acute and Chronic Systemic Toxicology Necropsy Equipment Preservation Procedure Special issues regarding gene-modified swine Resources Associations Books Journals Internet resources Swine and diet, and equipment Miniature Swine Resources Diet Resources References Index