The Laboratory Mouse

The Laboratory Mouse

Hardback Academic Press

Edited by Hans J. Hedrich

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  • Publisher: Academic Press Inc
  • Format: Hardback | 868 pages
  • Dimensions: 224mm x 276mm x 44mm | 2,681g
  • Publication date: 30 July 2012
  • Publication City/Country: San Diego
  • ISBN 10: 0123820081
  • ISBN 13: 9780123820082
  • Edition: 2, Revised
  • Edition statement: 2nd Revised edition
  • Illustrations note: Illustrations (chiefly col.)
  • Sales rank: 900,246

Product description

"The Laboratory Mouse, Second Edition" is a comprehensive book written by international experts. With inclusions of the newly revised European standards on laboratory animals, this will be the most current, global authority on the care of mice in laboratory research. This well-illustrated edition offers new and updated chapters including immunology, viruses and parasites, behavior, enrichment and care standards of laboratory mice across the life sciences, medical and veterinary fields. It features four-color illustrations with complete instruction on mouse surgery, anatomy, behavior and care of the mouse in laboratory research. It offers additional chapters on new mouse strains, phenotyping of strains, bacteria and parasites, and immunology. It includes the newly revised EU standards on care, as well as, comparisons to standards and regulations in the US and other countries.

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Review quote

"The Laboratory Mouse, 2nd Edition, deserves a place on the shelf of every laboratory animal medicine residency library and practitioner not only for its coverage of mouse biology and medicine, but also for its detailed descriptions of the emerging technologies and issues affecting the use of mice in research.My copy will get extensive use."--Laboratory Animal Practitioner, December 2013 "The book is enriched with excellent color figures and extensive literature.Researchers and students of the life science, medical and veterinary fields will find this book a necessary and useful tool."--Anticancer Research, Volume 33, Issue no. 5, May 2013 "In general, The Laboratory Mouse is well-written and easy to read. It is a useful resource for inexperienced as well as experienced scientists who use mice as experimental animals."--Lab Animal, April 2013

Table of contents

Part 1 History and Genetics 1.1 Origin and Phylogenetic Relationship of the Laboratory Mouse 1.2 Historical Foundations1.3 Strains, Stocks and Mutant Mice 1.4 Mouse Genomics 1.5 Generation of Mouse Mutants by Genotype-driven Mutagenesis Part 2 Anatomy and Normative Biology 2.1 Early Mouse Development2.2 Gross Anatomy2.3 Histology 2.4 Skin and Adnexa of the Laboratory Mouse 2.5 Development and Disease of Mouse Muscular and Skeletal Systems2.6 The Cardiovasular System 2.7 The Respiratory Tract 2.8 The Gastrointestinal System and Metabolism2.9 Hematology 2.10 Studying Immunology in Mice2.11Behaviour 2.12 Biological Rhythm of the Mouse Part 3 Neoplasms and Infectious Diseases 3.1 Diversity of Spontaneous Neoplasms in commonly used Inbred Strains of Laboratory Mice 3.2 Viral Infections 3.3 Bacterial Infections of the Laboratory Mouse3.4 Parasitic Infections of the Laboratory Mouse Part 4 Husbandry and Maintenance 4.1 Housing and Maintenance 4.2 Mouse Enrichment 4.3 Nutrition of the Laboratory Mouse4.4 Health Management and Monitoring4.5 Genetic Monitoring4.6 Gnotobiology and Breeding Techniques4.7 Cryopreservation of Pre-implantation Embryos and Gametes and associated Methods Part 5 Procedures 5.1 Handling and Restraint 5.2 Routes of Administration 5.3 Collection of Body Fluids 5.4 Anaesthesia, Analgesia and Euthanasia 5.5 Imaging the Laboratory Mouse in vivo 5.6 Necropsy Methods Part 6 Legal Regulations 6.1 Laws, Guidelines and Policies governing the Use of Mice in Research