Human Virology

Human Virology


By (author) Leslie Collier, By (author) John Oxford, By (author) Paul Kellam

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  • Publisher: Oxford University Press
  • Format: Paperback | 384 pages
  • Dimensions: 218mm x 272mm x 18mm | 1,021g
  • Publication date: 8 April 2011
  • Publication City/Country: Oxford
  • ISBN 10: 0199570884
  • ISBN 13: 9780199570881
  • Edition: 4, Revised
  • Edition statement: 4th Revised edition
  • Illustrations note: 150 colour line, 50 colour half-tone
  • Sales rank: 551,563

Product description

Viruses are the ultimate parasites: they infect cells and hijack their molecular machinery in order to survive, often destroying the host cell in the process. In so doing, they present a major challenge to human health and well-being, with the continual emergence of new viral strains placing huge demands on healthcare systems internationally. Human Virology is the perfect introduction to the subject for anyone who needs to understand how viruses impact on human health, and how they can be managed in a clinical context. It does not seek to turn its readers into virologists, but to provide them with enough knowledge of the nature of viruses and viral infections to serve as an essential foundation for anyone encountering viruses in a clinical or biomedical context. Capturing this complex and rapidly-evolving subject with remarkable clarity, Human Virology describes the general principles of viral biology - the properties of viruses, their replication and genetics - along with disease and resistance, before introducing the infections caused by key groups of viruses. It concludes with an overview of the management of viral disease, including diagnosis and immunization. Reflecting our latest understanding of the molecular basis of viral diseases, Human Virology is the ideal resource for all students of medicine, dentistry, and the biological and biomedical sciences, who need a clear and focused introduction to the subject. The Online Resource Centre to accompany Human Virology features: For lecturers: Figures from the book in electronic format For students: Hyperlinked bibliography that takes you directly to the articles mentioned in the textbook Oxford NewsNow - The latest news relevant to human virology Useful weblinks to help you research and revise

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Author information

Paul Kellam is Virus Genomics Team Leader at the Sanger Institute, Cambridge, and Reader in Host & Pathogen Interactions in the Department of Infection, MRC Centre for Medical Molecular Virology, University College London.

Review quote

Review from previous edition Covers all the bases well, with no major topic omitted. The authors' style is very "student friendly" and, sometimes, almost conversational in tone. This makes the book very easy to read. Layout is also user friendly with good use of tables/graphs/pictures. Reminders at each chapter end and appendices are also useful. Professor Kevin Kerr, Harrogate District Hospital. It is very comprehensive and covers most viruses that we encounter in clinical practice. I like the way how the chapters are divided into different types of viruses, its properties and clinical aspects of diseases. Chapter 7 is particularly useful as it mentions virus interaction in the community. Epidemiology is still an aspect that many people take for granted, but I think its an important element in virology. Dr Norzeihan Jan Bappu, Foundation 1 Doctor.

Table of contents

PART 1 GENERAL PRINCIPLPES ; 1. Virology: How it all began ; 2. General properties of viruses ; 3. Viral replication and genetics ; 4. How viruses cause disease ; 5. Resistance of the human body to virus infections ; 6. Viruses and cancer in humans ; 7. Viruses and the community ; PART 2 SPECIAL INFECTIONS ; 8. Upper respiratory tract and eye infections due to adenoviruses, coronaviruses (including SARS CoV), and rhinoviruses ; 9. Infections caused by paramyxoviruses: measles, RSV, mumps, parainfluenza, meta-pneumoviras and the henipaviruses ; 10. Orthomyxoviruses and influenza ; 11. Gastroenteritis viruses ; 12. Rubella: postnatal infections ; 13. Parvoviruses ; 14. Poxviruses ; 15. Papilloma - and polyomavirus ; 16. Poliomyelitis and other picornavirus infections ; 17. The herpesviruses: general properties ; 18. The alphaherpesviruses: herpes simplex and varicella-zoster ; 19. The betaherpesviruses: cytomegalovirus and human herpesviruses 6 and 7 ; 20. The gammaherpesviruses: Epstein-Barr virus and Kaposi's sarcoma-assocociated herpesvirus ; 21. Introduction to the hepatitis viruses ; 22. The blood-borne hepatitis viruses B and D ; 23. The blood-borne hepatitis C ; 24. The enteric hepatitis viruses A and E ; 25. Retroviruses and HIV ; 26. Lyssavirus and rabies ; 27. Arthropod-borne viruses ; 28. Exotic and dangerous infections: filoviruses and arenaviruses ; 29. Prions and the spongiform encephalopathies ; PART 3 SPECIAL SYNDROMES ; 30. Viral diseases of the central nervous system ; 31. Intrauterine and perinatal infections ; 32. Viral infections in patients with defective immunity ; 33. Respiratory Infections ; 34. Sexually transmitted viral infections ; 35. Resurgent and emergent viral infections ; PART 4 PRACTICAL ASPECTS ; 36. The laboratory diagnosis of viral infections ; 37. Control of viral diseases by immunization ; 38. Antiviral chemotherapy ; APPENDICES ; A SAFETY PRECAUTIONS: CODES OF PRACTICE, DISENFECTION, AND STERILIZATION ; B VIRAL INFECTIONS NOTIFIABLE IN THE UK ; C SUGGESTIONS FOR FUTHER READING ; INDEX