• Human Retroviruses

    Human Retroviruses (Hardback) Edited by Jerome E. Groopman, Edited by Etc., Edited by Irvin S.Y. Chen, Edited by Myron Essex, Edited by Robin A. Weiss


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    DescriptionHuman retrovirology is a rapidly advancing area of inquiry in medical microbiology and the study of infectious disease. This volume features recent information on human T cell leukemia viruses type 1 and 2 and on the two immunodeficiency-causing retroviruses, HIV-1 and HIV-2. In addition, it presents exploratory data on animal models of human retroviruses and the search for human retroviruses associated with multiple sclerosis and systemic lupus erythrematosis. The molecular biology of HTLV-1 is detailed, particularly the functions of the tax and rex proteins which have become a major focus, not only for the understanding of the function of this virus but also as models of gene regulation in eukaryotic cells. Similiarly, the molecular genetics and functional role products of HIV-1 and 2 are discussed at length.

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    Human Retroviruses
    Authors and contributors
    Edited by Jerome E. Groopman, Edited by Etc., Edited by Irvin S.Y. Chen, Edited by Myron Essex, Edited by Robin A. Weiss
    Physical properties
    Format: Hardback
    Number of pages: 434
    Width: 36 mm
    Height: 55 mm
    Weight: 850 g
    ISBN 13: 9780471567301
    ISBN 10: 0471567302

    BIC E4L: HEA
    Nielsen BookScan Product Class 3: S6.2
    BIC subject category V2: MJCJ, MMFM
    DC21: 616.0194
    BISAC V2.8: MED052000
    LC subject heading: , , , ,
    Illustrations note
    John Wiley and Sons Ltd
    Imprint name
    John Wiley & Sons Inc
    Publication date
    10 May 1990
    Publication City/Country
    New York
    Table of contents
    Partial table of contents:; MOLECULAR BIOLOGY OF HTLV; Control of Cellular and HTLV-I Gene Expression by Regulatory Genes (Tax and Rex) (M. Yoshida, et al.); Molecular Analysis of Trans-Activation in the HTLV-I LTR (S. Marriott, et al.); MOLECULAR BIOLOGY OF HIV; Functional and Structural Domains of the Human Immunodeficiency Virus Transacting Regulatory Proteins Tat and Rev (A. Cochrane, et al.); Transcriptional Regulation of HIV (B. Peterlin); VIRUS-CELL INTERACTIONS; Analysis of the HIV Envelope Binding Domain on CD4 Through Site-Directed Mutagenesis (J. Arthros, et al.); The Biologic Heterogeneity of HIV and the Pathogenesis of AIDS (J. Levy, et al.); STRATEGIES FOR VACCINE AND TREATMENT; Strategy of Targeted Antiretroviral Therapy Against Human Immunodeficiency Virus (HIV) (H. Mitsuya, et al.); Protection of Rabbits against HTLV-I Infection by Passive Immunization (N. Takehara, et al.); THE SEARCH FOR NEW HUMAN RETROVIRUSES; Evidence for the Involvement of Retroviruses in the Pathogenesis of Systemic Lupus Erythematosus (W. Leitmann, et al.); Evidence for Homologous Retroviral Sequences in Multiple Sclerosis by Enzymatic Gene Amplification (G. Ehrlich, et al.); Index.