• A Guide to Human Gene Therapy See large image

    A Guide to Human Gene Therapy (Hardback) Edited by Roland W. Herzog, Edited by Sergei Zolotukhin

    $112.40 - Save $24.85 18% off - RRP $137.25 Free delivery worldwide Available
    Dispatched in 2 business days
    When will my order arrive?
    Add to basket | Add to wishlist |

    DescriptionEver since the birth of molecular biology, the tantalizing possibility of treating disease at its genetic roots has become increasingly feasible. Gene therapy - though still in its infancy - remains one of the hottest areas of research in medicine. Its approach utilizes a gene transfer vehicle ( vector) to deliver therapeutic DNA or RNA to cells of the body in order to rectify the defect that is causing the disease. Successful therapies have been reported in humans in recent years such as cures in boys with severe immune deficiencies. Moreover, gene therapy strategies are being adapted in numerous biomedical laboratories to obtain novel treatments for a variety of diseases and to study basic biological aspects of disease. Correction of disease in animal studies, is steadily gaining ground, highlighting the immense potential of gene therapy in the medical profession. This book will cover topics that are at the forefront of biomedical research such as RNA interference, viral and non-viral gene transfer systems, treatment of hematological diseases and disorders of the central nervous system. Leading experts on the respective vector or disease will contribute the individual chapters and explain cutting-edge technologies. It also gives a broad overview of the most important gene transfer vectors and most extensively studied target diseases. This comprehensive guide is therefore a must-read for anyone in the biotechnology, biomedical or medical industries seeking to further their knowledge in the area of human gene therapy.


Other books

Other people who viewed this bought | Other books in this category
Showing items 1 to 10 of 10

 

Reviews | Bibliographic data
  • Full bibliographic data for A Guide to Human Gene Therapy

    Title
    A Guide to Human Gene Therapy
    Authors and contributors
    Edited by Roland W. Herzog, Edited by Sergei Zolotukhin
    Physical properties
    Format: Hardback
    Number of pages: 416
    Width: 158 mm
    Height: 232 mm
    Thickness: 23 mm
    Weight: 762 g
    Language
    English
    ISBN
    ISBN 13: 9789814280907
    ISBN 10: 9814280909
    Classifications

    Warengruppen-Systematik des deutschen Buchhandels: 16960
    BIC E4L: HEA
    Nielsen BookScan Product Class 3: S6.1T
    B&T Book Type: NF
    BIC subject category V2: PSD
    Ingram Subject Code: SE
    Libri: I-SE
    B&T Merchandise Category: SCI
    B&T Modifier: Text Format: 02
    B&T General Subject: 510
    B&T Modifier: Academic Level: 02
    Abridged Dewey: 616
    LC classification: RC
    BISAC V2.8: MED044000, SCI049000, SCI010000, MED107000, MED009000
    BIC subject category V2: MQW
    B&T Modifier: Region of Publication: 07
    BIC subject category V2: MJZ
    DC22: 615.895
    Thema V1.0: PSD, MQW, MKZV
    Edition
    1
    Illustrations note
    Illustrations (some col.)
    Publisher
    World Scientific Publishing Co Pte Ltd
    Imprint name
    World Scientific Publishing Co Pte Ltd
    Publication date
    30 June 2010
    Publication City/Country
    Singapore
    Flap copy
    Ever since the birth of molecular biology, the tantalizing possibility of treating disease at its genetic roots has become increasingly feasible. Gene therapy though still in its infancy remains one of the hottest areas of research in medicine. Its approach utilizes a gene transfer vehicle ("vector") to deliver therapeutic DNA or RNA to cells of the body in order to rectify the defect that is causing the disease. Successful therapies have been reported in humans in recent years such as cures in boys with severe immune deficiencies. Moreover, gene therapy strategies are being adapted in numerous biomedical laboratories to obtain novel treatments for a variety of diseases and to study basic biological aspects of disease. Correction of disease in animal studies, is steadily gaining ground, highlighting the immense potential of gene therapy in the medical profession. This book will cover topics that are at the forefront of biomedical research such as RNA interference, viral and non-viral gene transfer systems, treatment of hematological diseases and disorders of the central nervous system. Leading experts on the respective vector or disease will contribute the individual chapters and explain cutting-edge technologies. It also gives a broad overview of the most important gene transfer vectors and most extensively studied target diseases. This comprehensive guide is therefore a must-read for anyone in the biotechnology, biomedical or medical industries seeking to further their knowledge in the area of human gene therapy.
    Table of contents
    Non-Viral Vectors (S Sullivan); Adenoviral Vectors (A Baker); Retroviral Vectors and Integration Analysis (C von Kalle); Lentiviral Vectors (T VandenDriessche & M Chuah); Herpes Virus Vectors (J Glorioso); Adeno-Associated Viral (AAV) Vectors (N Muzyczka); Regulatory RNAs (Ribozymes, RNAi and miRNA) (A Lewin); Integrating Vectors (Transposon, Phage Integrase) (M Calos); Gene Correction Strategies/Zinc Fingers (M Porteus); Gene Switches (P Moullier); Gene Therapy for Disorders of the CNS (D Young); Hemoglobinopathies (A Srivastava); Severe Immune Deficiencies (A Aiuti); Hemophilia (R Herzog); Obesity and Diabetes (S Zolotukhin & C Wasserfall); Musculoskeletal Disorders (S Takeda); Cancer Gene Therapy (K Weigel-Van Aiken); Autoimmune Disorders (P Robbins); Lysosomal Storage Diseases (C Mah); Retinal Diseases (B Hauswirth); Pulmonary Diseases (T Flotte); Cardiovascular Diseases (B Byrne).