The GABA Receptors

The GABA Receptors

Hardback Receptors

By (author) S. J. Enna, By (author) Norman G. Bowery

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  • Publisher: Humana Press Inc.
  • Format: Hardback | 348 pages
  • Dimensions: 160mm x 228mm x 26mm | 721g
  • Publication date: 1 January 1997
  • Publication City/Country: Totowa, NJ
  • ISBN 10: 0896034585
  • ISBN 13: 9780896034587
  • Edition: 2, Revised
  • Edition statement: 2nd Revised edition
  • Illustrations note: 1

Product description

In this long-awaited 2nd edition of a classic book, leading neuroscientists critically review the latest advances made in our understanding of the fundamental molecular, biochemical, behavioral, and pharmacological properties of GABA receptors. The distinguished contributors clarify the approaches being taken to identify and develop new therapeutic agents for such neurological and psychiatric disorders as epilepsy, memory loss, affective illnesses, and psychosis. They also examine the therapeutic potential that remains in the cloning and expression of the GABA transporter, and in developing additional agents capable of regulating GABA receptor function. The book will play a key role in further expanding the list of drugs that interact with the GABA neurotransmitter system.

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Review quote

This is a very good summary of what is known on GABA receptors today and this is of great interest for neurobiologists, pharmacologists and neurophysiologists - ACTA Nuerologica Belgica

Table of contents

Structure and Function of GABA Reuptake Systems Baruch I. Kanner. Diversity in Structure Pharmacology and Regulation of GABAA Receptors H. Mhler D. Benke J. Benson B. L?scher U. Rudolph and J. M. Fritschy. GABAA Receptor Agonists Partial Agonists and Antagonists Povl Krogsgaard-Larsen Bente Fr>lund and Bjarke Ebert. Pharmacology of Mammalian GABAA Receptors Neil Upton and Thomas Blackburn. The Interaction of Intravenous Anesthetic Agents with Native and Recombinant GABAA Receptors: An Electrophysiological Study Jeremy J. Lambert Delia Belelli Marco Pistis Claire Hill- Venning and John A. Peters. Electrophysiology of GABAB Receptors Rudolf A. Deisz. Pharmacology of Mammalian GABAB Receptors Norman G. Bowery. Cellular and Biochemical Responses to GABAB Receptor Activation Martin Cunningham and S. J. Enna. Biochemical and Molecular Properties of GABAB Receptors Kinya Kuriyama and Masaaki Hirouchi. Chemistry of GABAB Modulators Wolfgang Froestl and Stuart J. Mickel. Molecular Biology Pharmacology and Physiology of GABAC Receptors Graham A. R. Johnston. Index.