Drug Eluting Stents

Drug Eluting Stents

Paperback

By (author) Sanjay Patel, By (author) Maulik Patel

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  • Publisher: LAP Lambert Academic Publishing
  • Format: Paperback | 124 pages
  • Dimensions: 152mm x 229mm x 7mm | 191g
  • Publication date: 24 July 2012
  • Publication City/Country: Saarbrucken
  • ISBN 10: 3659195820
  • ISBN 13: 9783659195822
  • Illustrations note: black & white illustrations

Product description

Interventional cardiologists have quickly replaced bare metal stents with intravascular drug-eluting stents (DES) for treating and preventing restenosis, largely on the basis of empirical evidence that shows profound reduction in angiographic and clinical restenosis. A critical reassessment of the published evidence, however, suggests that the putative superiority of intravascular drug-eluting stents is founded on questionable premises, including overestimation of restenosis benefit, underestimation of the risk for stent thrombosis, overreliance on "soft" rather than "hard" outcomes and the attendant overestimation of cost-effectiveness. Because the long-term incremental risks, benefits, and costs of drug-eluting stents have not yet been optimally evaluated in a broad spectrum of patient and lesion cohorts, the rational role of these devices in clinical management warrants reappraisal. This book will provide a brief overview of the development of drug-eluting stents from the laboratory bench to their investigation in clinical trials and their clinical use.

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Author information

Dr. Sanjay S. Patel, (Associate Professor, Pharmaceutics Department) and Dr. Natvarlal M. Patel (Principal) working in Shri B. M. Shah College of Pharmaceutical Education and Research, Modasa - 383315, India