Drug Discovery and Development: Technology in Transition

Drug Discovery and Development: Technology in Transition


By (author) Humphrey P. Rang

List price $70.31

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  • Format: Paperback | 360 pages
  • Dimensions: 193mm x 262mm x 23mm | 953g
  • Publication date: 4 January 2006
  • Publication City/Country: London
  • ISBN 10: 0443064202
  • ISBN 13: 9780443064203
  • Edition: 1
  • Illustrations note: Approx. 100 illustrations
  • Sales rank: 410,463

Product description

This book is highly commended in the medicine category in the BMA 2006 medical book competition! It is the winner of the Royal Society of Medicine Library Prize for Medical Book of the Year! Of the initial thousands of compounds with initial promise of drugs only a small handful be developed for human clinical trials and perhaps only one will become an approved drug. This book describes the huge complexities involved in bringing a drug to market and how new molecular understanding and techniques can make the process more targeted and successful.

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Table of contents

Section 1: Introduction: Development of the pharmaceutical industry Nature of disease and the purpose of therapy Therapeutic modalities Section 2: Drug discovery The drug discovery process: General principles and some case histories Choosing the project Choosing the target The role of genomics and bioinformatics High throughput screening The role of chemistry in the drug discovery process Pharmacokinetic issues in drug discovery Pharmacology: its role in drug discovery Biopharmaceuticals Patent issues in drug discovery Organisation of a large drug discovery department Section 3: Drug development: Introduction Assessing drug safety Pharmaceutical development Clinical development Protecting the assets: patenting and intellectual property Regulatory affairs Marketing the drug Section 4: Facts and figures: Drug discovery and development: Facts and figures