Development of Directly Compressible Co-Processed Excipients

Development of Directly Compressible Co-Processed Excipients

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By (author) Sanjay Patel, By (author) Dr Natvarlal M Patel

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  • Publisher: LAP Lambert Academic Publishing
  • Format: Paperback | 208 pages
  • Dimensions: 150mm x 220mm x 12mm | 358g
  • Publication date: 29 August 2011
  • Publication City/Country: Saarbrucken
  • ISBN 10: 3844398392
  • ISBN 13: 9783844398397
  • Illustrations note: black & white illustrations

Product description

Direct compression method in tableting is widely used due to fewer processing steps, simplified validation, elimination of heat and moisture, economy and improved drug stability. Hence, the current trend in the pharmaceutical industry is to adopt direct compression technology. Most of the drugs do not possess direct compression characteristic. Hence, development of various functionality added excipients (FAEs) to achieve formulations with desired effects is equally important. Excipients with improved functionality can be obtained by developing new chemical excipients, new grades of existing materials and new combination of existing materials. A much broader platform for the manipulation of excipient functionality is provided by co-processing or particle engineering of two or more excipients. The most important approach for controlling price for the excipients is to develop co-processed directly compressible excipients.

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Author information

Dr. Sanjay S. Patel, (Associate Professor, Pharmaceutics Department) and Dr. Natvarlal M. Patel (Principal) working in Shri B. M. Shah College of Pharmaceutical Education and Research, Modasa - 383315, India