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Critical Care Management for Laboratory Mice and Rats

Critical Care Management for Laboratory Mice and Rats

Paperback Laboratory Animal Pocket Reference

By (author) F. Claire Hankenson

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  • Publisher: CRC Press Inc
  • Format: Paperback | 271 pages
  • Dimensions: 160mm x 234mm x 15mm | 522g
  • Publication date: 5 November 2013
  • Publication City/Country: Bosa Roca
  • ISBN 10: 0849324998
  • ISBN 13: 9780849324994
  • Edition: 1
  • Edition statement: New ed.
  • Illustrations note: 69 colour illustrations, 20 black & white tables
  • Sales rank: 1,331,855

Product description

For critical care of laboratory rodents, there is a scarcity of sources for comprehensive, feasible, and response-oriented information on clinical interventions specific to spontaneous and induced models of disease. With the more complex cases that need critical care management, many treatment approaches to veterinary emergencies cannot be applied directly to the laboratory rodent. The first text of its kind devoted to the challenges of critical care management for laboratory rodents, Critical Care Management for Laboratory Mice and Rats provides a specialized resource for all veterinary, husbandry, technical, and research professionals who utilize rodent models for biomedical research. The book covers the varied approaches to laboratory rodent patient care, health assessments, characteristics of specific disease models, monitoring and scoring of disease parameters, and humane interventions. Giving primary consideration to preservation of animal health and welfare, the text also considers how best to balance welfare with the achievement of proposed scientific objectives. Organized into five chapters, this full-color book covers the following topics: General Approaches for Critical Care Critical Care Management for Laboratory Mice Critical Care Management for Laboratory Rats Special Considerations for Critical Care Management in Laboratory Rodents Resources and Additional Information The author provides treatment guidelines with the expectation that they will be applied with apt professional judgment, allowing for further modification of clinical recommendations for improved patient-based care and welfare for research animals.

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Author information

F. Claire Hankenson, DVM, MS, is the senior associate director in University Laboratory Animal Resources, University of Pennsylvania, Philadelphia, and is an associate professor of laboratory animal medicine in the Department of Pathobiology at the School of Veterinary Medicine. Dr. Hankenson obtained her veterinary degree from Purdue University. Following veterinary school, she completed her laboratory animal medicine residency and graduate work (MS, microbiology) at the University of Washington, Seattle. She became a Diplomate of the American College of Laboratory Animal Medicine (ACLAM) in 2002. Her own research studies involve investigations of refinements in the care and use of laboratory rodents, particularly blood sampling, tail biopsy evaluations, and humane endpoints.

Table of contents

general approaches for critical care overview obtaining a clinical history and medical records body condition scoring relocation for physical examinations monitoring critically ill rodents pain recognition and assessments supportive care for surgical procedures supplemental heat provision drug therapy references critical care management for laboratory mice introduction overall assessments general medical approaches to physical examination and health assessments veterinary care measures abnormal, critical, and emergent conditions research-related medical issues euthanasia references critical care management for laboratory rats introduction overall assessments general medical approaches to physical examination and health assessments veterinary care measures abnormal, critical, and emergent conditions research-related medical issues euthanasia references special considerations for critical care management in laboratory rodents introduction aging animal model considerations blood loss considerations chronic indwelling device considerations depilatory cream considerations equipment considerations for rodent surgery and emergency procedures euthanasia considerations experimental autoimmune encephalomyelitis and demyelinating disease model considerations fasting considerations fluid therapy considerations food and fluid regulation procedures humane or "clinical" endpoint considerations nutritional therapy considerations perioperative care considerations regulatory considerations restraint collar considerations tracheostomy considerations tumor development and monitoring considerations wound management considerations references resources and additional information introduction organizations publications electronic resources commercial resources appendix A: glossary of acronyms and terms appendix B: suggested medical supplies for rodent critical care appendix C: rodent formulary Index