Basic and Clinical Pharmacology

Basic and Clinical Pharmacology

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The most up-to-date, comprehensive, and authoritative pharmacology text in health medicine Enhanced by more than three hundred illustrations -- many in full color Organized to reflect the syllabi in many pharmacology courses and in integrated curricula, Basic & Clinical Pharmacology, 12e covers the important concepts students need to know about the science of pharmacology and its application to clinical practice. Selection of the subject matter and order of its presentation are based on the authors' many years experience in teaching this material to thousands of medical, pharmacy, dental, podiatry, nursing, and other health science students. To be as clinically relevant as possible, the book includes sections that specifically address the clinical choice and use of drugs in patients and the monitoring of their effects, and case studies that introduce clinical problems in many chapters. Presented in full color and enhanced by more than three hundred illustrations, Basic & Clinical Pharmacology features numerous summary tables and diagrams that encapsulate important information. Coverage that spans every aspect of medical pharmacology: Basic principles Autonomic drugs Cardiovascular-renal drugs Drugs with important actions on smooth muscles Central nervous system drugs Drugs used to treat anemias, clotting disorders, hyperlipidemia, and inflammation and gout Endocrine drugs Chemotherapeutic and immunologic drugs Toxicology Special subjects (perinatal, geriatric, and dermatologic pharmacology) Botanical and "food supplements," and over-the-counter medications Prescribing Also in this edition: Drug Summary Tables conclude most chapters, providing a concise summary of the most important drugs General concepts relating to newly discovered receptors, receptor mechanisms, and drug transporters Descriptions of important new drugs, including monoclonal antibodiesshow more

Product details

  • Paperback | 1248 pages
  • 215.9 x 274.32 x 40.64mm | 2,517.42g
  • McGraw-Hill Education - Europe
  • McGraw-Hill Medical
  • New York, United States
  • English
  • Revised
  • 12th Revised edition
  • col. ill
  • 0071764011
  • 9780071764018
  • 43,537

Table of contents

Section I. Basic Principles 1 Introduction 2 Drug Receptors & Pharmacodynamics 3 Pharmacokinetics & Pharmacodynamics: Rational Dosing & the Time Course of Drug Action 4 Drug Biotransformation 5 Basic & Clinical Evaluation of New Drugs Section II. Autonomic Drugs 6 Introduction to Autonomic Pharmacology 7 Cholinoceptor-Activating & Cholinesterase-Inhibiting Drugs 8 Cholinoceptor-Blocking Drugs 9 Adrenoceptor-Activating & Other Sympathomimetic Drugs 10 Adrenoceptor Antagonist Drugs Section III. Cardiovascular-Renal Drugs 11 Antihypertensive Agents 12 Vasodilators & the Treatment of Angina Pectoris 13 Drugs Used in Heart Failure 14 Agents Used in Cardiac Arrhythmias 15 Diuretic Agents Section IV. Drugs With Important Actions on Smooth Muscle 16 Histamine, Serotonin, & the Ergot Alkaloids 17 Vasoactive Peptides 18 The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & Related Compounds 19 Nitric Oxide, Donors, & Inhibitors 20 Drugs Used in Asthma Section V. Drugs That Act In The Central Nervous System 21 Introduction to the Pharmacology of CNS Drugs 22 Sedative-Hypnotic Drugs 23 The Alcohols 24 Antiseizure Drugs 25 General Anesthetics 26 Local Anesthetics 27 Skeletal Muscle Relaxants 28 Pharmacologic Management of Parkinsonism & Other Movement Disorders 29 Antipsychotic Agents & Lithium 30 Antidepressant Agents 31 Opioid Analgesics & Antagonists 32 Drugs of Abuse Section VI. Drugs Used to Treat Diseases of the Blood, Inflammation & Gout 33 Agents Used in Anemias; Hematopoietic Growth Factors 34 Drugs Used in Disorders of Coagulation 35 Agents Used in Hyperlipidemia 36 Nonsteroidal Anti-Inflammatory Drugs, Disease-Modifying Section VII. Endocrine Drugs 37 Hypothalamic & Pituitary Hormones 38 Thyroid & Antithyroid Drugs 39 Adrenocorticosteroids & Adrenocortical Antagonists 40 The Gonadal Hormones & Inhibitors 41 Pancreatic Hormones & Antidiabetic Druigs 42 Agents That Affect Bone Mineral Homeostasis Section VIII. Chemotherapeutic Drugs 43 {b}-Lactam Antibiotics & Other Inhibitors of Cell Wall Synthesis 44 Chloramphenicol,Tetracyclines, Macrolides, Clindamycin, & Streptogramins 45 Aminoglycosides & Spectinomycin 46 Sulfonamides, Trimethoprim, & Quinolones 47 Antimycobacterial Drugs 48 Antifungal Agents 49 Antiviral Agents 50 Miscellaneous Antimicrobial Agents; Disinfectants, Antiseptics, & Sterilants 51 Clinical Use of Antimicrobial Agents 52 Antiprotozoal Drugs 53 Clinical Pharmacology of the Anthelmintic Drugs 54 Cancer Chemotherapy 55 Immunopharmacology Section IX. Toxicology 56 Introduction to Toxicology: Occupational & Environmental 57 Heavy Metal Intoxication & Chelators 58 Management of the Poisoned Patient § Section X. Special Topics 69 Special Aspects of Perinatal & Pediatric Pharmacology 60 Special Aspects of Geriatric Pharmacology 61 Dermatologic Pharmacolgy 62 Drugs Used in the Treatment of Gastrointestinal Diseases 63 Therapeutic & Toxic Potential of Over-the-Counter Agents 64 Botanicals ( Herbal Medications ) & Nutritional Supplements 65 Rational Prescribing & Prescription Writing 66 Important Drug Interactions & Their Mechanisms App I Vaccines, Immune Globulins, & Other Complex Biologic Productsshow more