Apoptosis: The Molecular Biology of Programmed Cell Death (Paperback)
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Short Description for Apoptosis This work is intended for postgraduate students in cell biology, postdoctoral researchers new to the field, advanced undergraduates, postgraduate medical students, and clinicians undertaking research training in the area.
- Published: 20 June 2002
- Format: Paperback 346 pages
- ISBN 13: 9780199638499 ISBN 10: 0199638497
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Full description for Apoptosis
Apoptosis is a regulated form of cell demise that can be induced or blocked by groups of specific stimuli. Occurring in all living tissues, it is thought critical to the maintenance of homeostasis and is implicated in lowering susceptibility to tumour growth. Conversely, over-sensitivity to apoptotic triggers can cause cells to be lost inappropriately from tissues, as appears to occur in neurodegenerative diseases. This book examines the molecular pathways regulating apoptosis, progressing from the nematode worm through Drosphila to the more complex pathways evident in mammalian cells. Differences in the cell death pathway within specific tissues are addressed, as are the different genes that may act to regulate progressive steps.