The Antidote: Inside the World of New Pharma

The Antidote: Inside the World of New Pharma


By (author) Barry Werth

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  • Publisher: SIMON & SCHUSTER
  • Format: Hardback | 448 pages
  • Dimensions: 170mm x 239mm x 46mm | 612g
  • Publication date: 4 February 2014
  • Publication City/Country: New York
  • ISBN 10: 1451655665
  • ISBN 13: 9781451655667
  • Sales rank: 542,832

Product description

The $325 billion-a-year pharmaceutical business is America's most challenging and one of its most profitable. It is tougher in just about every way than any other enterprise: from the towering biological risks inherent in its mission to treat disease; to the thirty-to-one failure rate in bringing out a successful medicine after a candidate clears all the hurdles to get to human testing; to the billion-dollar-plus cost of ramping up a successful product; to operating in the world's most highly regulated industry with the possible exception of nuclear power. The Antidote tells the story of Vertex, a maverick drug company led by the charismatic Joshua Boger and a small group of entrepreneurial young scientists who broke off from Merck when it was the world's best drug maker-indeed the most admired business in America-because they thought they could make drugs better. Building upon his widely praised The Billion-Dollar Molecule, Barry Werth captures the full scope of Vertex's twenty-five-year drive to deliver breakthrough medicines and transform the drug industry. The Antidote draws upon unprecedented inside reporting spanning more than two decades to provide a ground-breaking close-up of Vertex's inner workings and the ferocious but indispensable world it inhabits.

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Author information

Barry Werth is an award-winning journalist and the acclaimed author of five books. His articles have appeared in The New Yorker, The New York Times Magazine, and GQ, among others. He has taught at Smith, Mount Holyoke, and Boston University. His previous book on Vertex, The Billion-Dollar Molecule, was selected as one of Fortune's "75 Smartest Books We Know."